Background: Viral pneumonia is the main type of community-acquired pneumonia (CAP) in children. YKL-40, a\nchitinase-like protein, is regarded as a biomarker of the degree of inflammation.\nMethods: Children who were diagnosed with CAP, including viral pneumonia, bacterial pneumonia, and dual\ninfection, were included in the cohort study. The pathogenic diagnosis depended on PCR and immunoassay test.\nYKL-40 levels were examined twice by enzyme-linked immunoassay (ELISA).\nResults: Serum YKL-40 levels were higher in patients with pneumonia than in healthy controls. The admission\nlevels of YKL-40 in serum and Bronchoalveolar lavage (BALFs) indicated a positive correlation with the serum levels\nof C-reactive protein and other inflammatory cytokines (IL-6 and TNF�������.
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